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In the presence of ATP, molecular motors generate active force dipoles thatdrive suspensions of protein filaments far from thermodynamic equilibrium,leading to exotic dynamics and pattern formation. Microscopic modelling canhelp to quantify the relationship between individual motors plus filaments toorganisation and dynamics on molecular and supra-molecular length scales. Herewe present results of extensive numerical simulations of active gels where themotors and filaments are confined between two infinite parallel plates. Thermalfluctuations and excluded-volume interactions between filaments are included. Asystematic variation of rates for motor motion, attachment and detachment,including a differential detachment rate from filament ends, reveals a range ofnon-equilibrium behaviour. Strong motor binding produces structured filamentaggregates that we refer to as asters, bundles or layers, whose stabilitydepends on motor speed and differential end-detachment. The gross features ofthe dependence of the observed structures on the motor rate and the filamentconcentration can be captured by a simple one-filament model. Loosely boundaggregates exhibit super-diffusive mass transport, where filament translocationscales with lag time with non-unique exponents that depend on motor kinetics.An empirical data collapse of filament speed as a function of motor speed andend-detachment is found, suggesting a dimensional reduction of the relevantparameter space. We conclude by discussing the perspectives of microscopicmodelling in the field of active gels.

Non-equilibrium structure and dynamics in a microscopic model of thin film active gels