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In this paper we present a method for the real-time detection of the bases ofthe deoxyribonucleic acid using their signatures in negative differentialconductance measurements. The present methods of electronic detection ofdeoxyribonucleic acid bases are based on a statistical analysis because theelectrical currents of the four bases are weak and do not differ significantlyfrom one base to another. In contrast, we analyze a device that combines theaccumulated knowledge in nanopore and scanning tunneling detection, and whichis able to provide very distinctive electronic signatures for the four bases.

Real-Time Detection of Deoxyribonucleic Acid Bases via their Negative Differential Conductance Signature