English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Living cells employ excitable reaction-diffusion waves for internal cellularfunctions, in which curvature-inducing proteins are often involved. However,the role of their mechanochemical coupling is not well understood. Here, wereport the membrane deformation induced by the excitable reaction-diffusionwaves of curvature-inducing proteins and the alternation in the waves due tothe deformation, using a coarse-grained simulation of tubular membranes with amodified FitzHugh--Nagumo model. Protein-propagating waves deform tubularmembranes, and large deformations induce budding and erase waves. The wavespeed and shape are determined by a combination of membrane deformation andspatial distribution of the curvature-inducing protein. Waves are alsoundulated in the azimuthal direction depending on the condition. Rotationallysymmetric waves locally deform the tubes into a symmetric shape but maintain astraight shape on average. Our simulation method can be applied to otherchemical reaction models and used to investigate various biomembrane phenomena.

Excitable reaction-diffusion waves of curvature-inducing proteins on deformable membrane tubes