English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

This work introduces a methodology for the statistical mechanical analysis ofpolymeric chains under tension controlled by optical or magnetic tweezers atthermal equilibrium with an embedding fluid medium. The response of singlebonds between monomers or of entire groups of monomers to tension is governedby the activation of statistically interacting particles representing quanta ofextension or contraction. This method of analysis is capable of describingthermal unbending of the freely jointed or wormlike chain kind, linear ornonlinear contour elasticity, and structural transformations including effectsof cooperativity. The versatility of this approach is demonstrated in anapplication to double-stranded DNA undergoing torsionally unconstrainedstretching across three regimes of mechanical response including anoverstretching transition. The three-regime force-extension characteristic,derived from a single free-energy expression, accurately matches empiricalevidence.

Molecular chains under tension: Thermal and mechanical activation of statistically interacting extension and contraction particles