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The cosmic-ray flux of antiprotons is measured with high precision by thespace-borne particle spectrometers AMS-02.Its interpretation requires a correctdescription of the dominant production process for antiprotons in our Galaxy,namely, the interaction of cosmic-ray proton and helium with the interstellarmedium. In the light of new cross section measurements by the NA61 experimentof $p + p \rightarrow \bar{p} + X$ and the first ever measurement of $p +\mathrm{He} \rightarrow \bar{p} + X$ by the LHCb experiment, we update theparametrization of proton-proton and proton-nucleon cross sections.We find thatthe LHCb $p$He data constrain a shape for the cross section at high energiesand show for the first time how well the rescaling from the $pp$ channelapplies to a helium target. By using $pp$, $p$He and $p$C data we estimate theuncertainty on the Lorentz invariant cross section for $p + \mathrm{He}\rightarrow \bar{p} + X$. We use these new cross sections to compute the sourceterm for all the production channels, considering also nuclei heavier than Heboth in cosmic rays and the interstellar medium. The uncertainties on the totalsource term are at the level of $\pm20$% and slightly increase below antiprotonenergies of 5 GeV. This uncertainty is dominated by the $p+p \rightarrow\bar{p} + X$ cross section, which translates into all channels since we derivethem using the $pp$ cross sections. The cross sections to calculate the sourcespectra from all relevant cosmic-ray isotopes are provided in the SupplementalMaterial. We finally quantify the necessity of new data on antiprotonproduction cross sections, and pin down the kinematic parameter space whichshould be covered by future data.

Production cross sections of cosmic antiprotons in the light of new data from the NA61 and LHCb experiments