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In the perturbative QCD (PQCD) approach we study the direct $CP$ violation in$B^+_{c}\rightarrow D_{(s)}^+\rho^0(\omega) \rightarrow D_{(s)}^+\pi^+\pi^-$via the $\rho-\omega$ mixing mechanism. We find that the $CP$ violation can beenhanced by $\rho-\omega$ mixing when the invariant masses of the $\pi^+\pi^-$pairs are in the vicinity of the $\omega$ resonance. For the decay process$B^+_{c}\rightarrow D^+\rho^0(\omega) \rightarrow D^+\pi^+\pi^-$, the maximum$CP$ violation can reach 7.5 {\%}.

$CP$ violation for $B^+_{c}\rightarrow D_{(s)}^+\pi^+\pi^-$ in Perturbative QCD