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We determine the decay constants of the pi and K mesons on gluon fieldconfigurations from the MILC collaboration including u, d, s and c quarks. Weuse three values of the lattice spacing and u/d quark masses going down to thephysical value. We use the w_0 parameter to fix the relative lattice spacingand f_pi to fix the overall scale. This allows us to obtain a value forf{K^+}/f{pi^+} = 1.1916(21). Comparing to the ratio of experimental leptonicdecay rates gives |Vus| = 0.22564(28){Br(K^+)}(20){EM}(40){latt}(5){Vud} andthe test of unitarity of the first row of the Cabibbo-Kobayashi-Maskawa matrix:|Vud|^2+|Vus|^2+|Vub|^2 - 1 = 0.00009(51).

Vus from pi and K decay constants in full lattice QCD with physical u, d, s and c quarks