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We calculate the two loop contribution to the predictions of the mass scalesin an SO(10) grand unified theory. We consider the modified unification scaleboundary conditions due to the non-renormalizable higher dimensional termsarising from quantum gravity or spontaneous compactification of extradimensions in Kaluza-Klein type theory. We find the range of these couplingswhich allows left-right symmetry to survive till very low energy (as low as$\sim$ TeV) and still be compatible with the latest values of $\sin^2 \theta_W$and $\alpha_s$ derived from LEP. We consider both the situation when theleft-right parity is broken and conserved.We consider both supersymmetric andnon-supersymmertic versions of the SO(10) theory.Taking the D-conservednon-susy case as an example we calculate the effects of moderate thresholduncertainties at the heavy scale, due to the unknown higgs masses,on thegravity induced couplings.Comment: 18 pages with three figures available on  request(datta@uhhepg.bitnet),UH-511-780-9

Corrections to mass scale predictions in SO(10) grand unified theory with higher dimensional operators