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Two-dimensional quantum spin Hall (QSH) insulators with reasonably wide bandgaps are imperative for the development of various innovative technologies.Through systematic density functional calculations and tight-bindingsimulations, we found that stanene on {\alpha}-alumina surface may possess asizeable topologically nontrivial band gap (~0.25 eV) at the {\Gamma} point.Furthermore, stanene is atomically bonded to but electronically decoupled fromthe substrate, providing high structural stability and isolated QSH states to alarge extent. The underlying physical mechanism is rather general, and thisfinding may lead to the opening of a new vista for the exploration of QSHinsulators for room temperature device applications.

Possibility of Realizing Quantum Spin Hall Effect at Room Temperature in Stanene/Al2O3(0001)