Open AccessInnate and adaptive immune response to chronic pulmonary infection of hyphae of Aspergillus fumigatus in a new murine model
Author(s) -
Fengyuan Wang,
Caiyun Zhang,
Yuan Jiang,
Cai-Xia Kou,
Qingtao Kong,
Nanbiao Long,
Ling Lü,
Hong Sang
Publication year - 2017
Publication title -
journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000590
Subject(s) - hypha , aspergillus fumigatus , lung , pathogenesis , immune system , biology , microbiology and biotechnology , immunology , conidium , pathology , infiltration (hvac) , medicine , materials science , genetics , composite material
The pathogenesis of chronic pulmonary aspergillosis (CPA) has seldom been studied due partly to a lack of animal models. Since hypha is the main morphology colonizing the airway in CPA, it's critical to study the immune reaction to chronic pulmonary infection of hyphae of Aspergillus fumigatus, which also has seldom been studied in vivo before.
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