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SUMMARY: Evidence suggesting that the flagella of the highly immunogenic Clostridium chauvoei, strain ch3, may be important in stimulating protective immunity was studied by preparing a pure flagellar suspension from the organism and comparing the protective antigenicity of the flagellar suspension and deflagellated cells. The protective antigenicity of strain ch3 was not of flagellar origin, but due to a heat labile, pH sensitive, non-agglutinogenic somatic antigen.

The Protective Antigen of a Highly Immunogenic Strain of Clostridium chauvoei Including an Evaluation of Its Flagella as a Protective Antigen