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A temperate bacteriophage named ‘tau’ which forms plaques on F- strains but not on F+strains of Escherichia colik 12 has been isolated. This phage adsorbs equally well to F+ and F-strains, which indicates that some later step of the growth cycle is inhibited by the presence of the sex-factor F. The frequency of lysogenization of the phage is also affected by the F factor. The genetic material of phage tau may be DNA. The phage is 40–50 mμ in diameter.

A Temperate Phage Specific for Female Strains of Escherichia coli k 12