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Piry rhabdovirus is not transmitted from Drosophila melanogaster females to their progeny. However, in mixed infections with sigma, another rhabdovirus, bearing the g+ genetic marker, Piry may occasionally be transmitted to offspring. Thus, an endemic Drosophila virus can act as a helper virus enabling vertical transmission of a virus pathogenic to vertebrates.

Vertical Transmission of the Piry Rhabdovirus by Sigma Virus-Infected Drosophila melanogaster Females