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SUMMARY Serial undiluted passages of vesicular stomatitis virus in African green monkey kidney (CV-1) cells resulted in the generation of a small-plaque-forming mutant. This mutant has been characterized as a non-defective particle with homotypic and heterotypic interference properties.

Generation and Characterization of a Non-defective Interfering Particle of Vesicular Stomatitis Virus: Homotypic and Heterotypic Interference