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A cell line resistant to ethidium bromide has been developed from baby hamster kidney cells transformed by Rous sarcoma virus. The parental cells are normally non-producers but the resistant cell line appears to produce virus-like particles that are associated with the mitochondria as visualized by electron microscopy and determined biochemically.

Virus-like Particles Associated with the Mitochondria of Ethidium Bromide Treated Transformed Cells