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The effect of virion age on the two A and B 8 S RNA conformational isomers was investigated by electrophoresis on polyacrylamide gels. The relative proportions of A and B 8 S RNA components of the immature virus (rapid harvest, 30 min) are intermediate between those previously found for the mature virus and for the host cell. These results suggest that a change of 8S RNA conformation occurs during virus maturation.

Effect of Murine Leukaemia Virus Age on its 8S RNA Components