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After the observations and experiments made by Dr. Pearson, to investigate the nature of Dr. Jamesʼs Powder, and presented by him to this Society, very little remained to be effected or desired, towards a further knowledge of the subject. But those very experiments served to suggest, that the mode of preparation was far from being the best that the present improved state of chymical knowledge might afford; and that, in all probability, a less defective composition might result from a process more conformable to some improvements, which of late have been advantageously applied to pharmaceutic chymistry. It may be laid down as a general principle, that, in delicate experiments, whether analytical or synthetical, fire (that potent and once believed to be universal agent) is too precarious in its means, and too uncertain in its application, to be employed with full and constant success. And, if it is still recurred to, the advantage of promptness, and a remnant of ancient custom, are the principal reasons. But, where other methods can be devised to effect the same combinations, (and the humid way offers many,) every person conversant in chymical knowledge will allow the benefit of adopting them. The recent improvement in the mode of preparing calomel, is a striking example of such salutary corrections being successfully introduced.

XVIII. Observations and experiments upon Dr. Jamesʼs powder; with a method of preparing, in the humid way, a similar substance