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Having for some time been engaged in an investigation of the question as to how far the fibres of each pyramid descend both halves of the spinal cord, I am in a position to state that in the bonnet monkey (Macacus sinicus ) the following arrangement prevails.Method of Investigation .—The animal being etherised, and the left hemisphere of the brain exposed by a single trephine hole (sometimes enlarged afterwards), a small portion of the excitable area of the motor cortex was selected as detailed below, the selection being confirmed in each case by electrical stimulation. A small piece of the cortex, about 0.4 cm. square, constituting the focus of the movement observed, was removed, care being taken to remove also a little of the underlying corona radiata to be sure that no cortex was left.

I. Preliminary note on bilateral degeneration in the spinal cord of monkeys ( Macacus sinicus ) following unilateral lesion of the cortex cerebri