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The canal, which is the subject of this letter, appears to have been discovered by the author in the year 1803, although no account has been given of it till the present description was drawn up at the request of Mr. Home. From the extremity of the sixth ventricle of the brain in the horse, bullock, sheep, hog, and dog (which corresponds to the fourth ventricle in the human subject), a canal passes in a direct course to the centre of the spinal marrow, and may be discovered in its course by a transverse section of the spinal marrow in any part of its length, having a diameter sufficient to admit a large-sized pin; and it is proved to be a continued tube, from one extremity to the other, by the passage of quicksilver in a small stream in either direction through it.

A letter on a canal in the medulla spinalis of some quadrupeds. In a letter from Mr. William Sewell, to Everard Home, Esq. F. R. S