Open AccessHarnessing nature's toolbox: regulatory elements for synthetic biology
Author(s) -
Patrick M. Boyle,
Pamela A. Silver
Publication year - 2009
Publication title -
journal of the royal society interface
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 139
eISSN - 1742-5689
pISSN - 1742-5662
DOI - 10.1098/rsif.2008.0521.focus
Subject(s) - synthetic biology , modularity (biology) , modular design , toolbox , systems biology , computational biology , computer science , biological network , biology , biochemical engineering , data science , engineering , evolutionary biology , programming language , operating system
Synthetic biologists seek to engineer complex biological systems composed of modular elements. Achieving higher complexity in engineered biological organisms will require manipulating numerous systems of biological regulation: transcription; RNA interactions; protein signalling; and metabolic fluxes, among others. Exploiting the natural modularity at each level of biological regulation will promote the development of standardized tools for designing biological systems.
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