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Tacrolimus is one of the most commonly used immunosuppressive drugs but tacrolimus-induced severe symptomatic hyponatremia is not a well-documented issue in kidney transplant patients.1–4 In our current report, we describe a case of tacrolimus-induced hyponatremia in a living donor kidney recipient in whom any other potential cause of hyponatremia was excluded, and tacrolimus-induced salt losing nephropathy was resolved after conversion to everolimus.

Tacrolimus-Induced Salt Losing Nephropathy Resolved After Conversion to Everolimus