Open AccessHigh Tidal Volume Ventilation Is Not Deleterious in Infant Rats Exposed to Severe Hemorrhage
Author(s) -
Vincenzo Cannizzaro,
Luke J. Berry,
Philip K. Nicholls,
Zoltán Hantos,
Peter D. Sly
Publication year - 2010
Publication title -
journal of trauma and acute care surgery
Language(s) - English
Resource type - Journals
eISSN - 1529-8809
pISSN - 0022-5282
DOI - 10.1097/ta.0b013e3181d7503c
Subject(s) - medicine , tidal volume , ventilation (architecture) , anesthesia , bronchoalveolar lavage , positive end expiratory pressure , resuscitation , mechanical ventilation , respiratory system , lung , mechanical engineering , engineering
Both high tidal volume (V(T)) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung injury in infant rats exposed to severe hemorrhage.
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