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To determine if observation alone after nephrectomy in very low-risk Wilms tumor (defined as stage I favorable histology Wilms tumors with nephrectomy weight &lt;550g and age at diagnosis &lt;2 years) results in satisfactory event-free survival and overall survival, and to correlate relapse with biomarkers.

Clinical Outcome and Biological Predictors of Relapse After Nephrectomy Only for Very Low-risk Wilms Tumor