Open AccessDifferential Associations of Specific Selective Serotonin Reuptake Inhibitors With Resting-State Heart Rate and Heart Rate Variability: Implications for Health and Well-Being
Author(s) -
Andrew H. Kemp,
Renério Fráguas,
André R. Brui,
Márcio Sommer Bittencourt,
Maria Angélica Nunes,
Eduardo Miranda Dantas,
Rodrigo Varejão Andreão,
José Geraldo Mill,
Antônio Luiz Pinho Ribeiro,
Julian Koenig,
Julian F. Thayer,
Isabela M. Benseñor,
Paulo A. Lotufo
Publication year - 2016
Publication title -
psychosomatic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.62
H-Index - 187
eISSN - 1534-7796
pISSN - 0033-3174
DOI - 10.1097/psy.0000000000000336
Subject(s) - sertraline , citalopram , escitalopram , paroxetine , fluoxetine , confounding , heart rate variability , serotonin reuptake inhibitor , propensity score matching , antidepressant , psychology , reuptake inhibitor , medicine , serotonin uptake inhibitors , heart rate , psychiatry , serotonin , anxiety , receptor , blood pressure
Debate has focused on the effects of the selective serotonin reuptake inhibitor (SSRI) antidepressants on heart rate (HR) and HR variability (HRV), both of which are predictors of adverse cardiovascular events. Here, we examine the associations between specific SSRI antidepressants and resting state HR (and HRV) after accounting for a host of potential confounding factors using propensity score techniques.
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