Open AccessEmergence of Increased Azithromycin Resistance During Unsuccessful Treatment of Neisseria gonorrhoeae Infection With Azithromycin (Portland, OR, 2011)
Author(s) -
Olusegun O. Soge,
Doug Harger,
Sean Schafer,
Kim Toevs,
K. Raisler,
Kathy Venator,
King K. Holmes,
Robert D. Kirkcaldy
Publication year - 2012
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0b013e3182685d2b
Subject(s) - azithromycin , neisseria gonorrhoeae , medicine , gonorrhea , sexually transmitted disease , antibiotic resistance , antibiotics , microbiology and biotechnology , virology , syphilis , human immunodeficiency virus (hiv) , biology
We describe the emergence of an azithromycin-resistant Neisseria gonorrhoeae variant in a man from Portland, Oregon, during sole treatment with 2 g azithromycin. This report highlights the ease with which gonococcal macrolide resistance can emerge, the threat of multidrug resistant N. gonorrhoeae, and the need for adherence to Centers for Disease Control and Prevention treatment guidelines.