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Background:  Postoperative sore throat (POST) following general anesthesia with endotracheal intubation is a common complication. We hypothesized that lidocaine jelly applied to the tapered cuff of the endotracheal tube (ETT) might decrease the incidence of POST most commonly arising from endotracheal intubation.    Methods:  A total of 208 patients under general anesthesia were randomly assigned into 1 of 2 groups. In the lidocaine group (n = 104), the distal part of ETTs with tapered-shaped cuff was lubricated with lidocaine jelly. In the control group (n = 104), the distal part of ETTs with tapered-shaped cuff was lubricated with normal saline. The incidence of POST, hoarseness, and cough in the postanesthesia patients was compared.    Results:  The overall incidence of POST was higher in the lidocaine group than in the normal saline group [60 (58%) vs 40 (39%),  P  = .006]. The incidence of POST at 1 hour postoperatively was higher in the lidocaine group than in the normal saline group [53 (51%) vs 32 (31%),  P  = .003]. The overall incidence of hoarseness for 24 hours postoperatively was comparable ( P  = .487). The overall incidence of cough for 24 hours postoperatively is higher in the lidocaine group ( P  = .045).    Conclusion:  The lidocaine jelly applied at the distal part of ETT with tapered-shaped cuff increased the overall incidence of POST in patients undergoing general anesthesia.

The effect of lidocaine jelly on a taper-shaped cuff of an endotracheal tube on the postoperative sore throat