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indicating better function) were evaluated longitudinally through five years. Patients who did not complete at least one CES-D or SF-36 follow-up survey were excluded from the analysis. Univariate and multivariate analysis were performed to assess factors associated with CES-D and SF-36 scores. RESULTS: Among 1509 (52.4%) patients undergoing radical prostatectomy, 961 (33.4%) undergoing radiation therapy and 409 (14.2%) undergoing active surveillance there were no significant differences in CES-D or SF-36 scores between treated patients and those undergoing active surveillance (Table 1). The most significant predictors of decline in CES-D score included: older age (p[0.0075), poor overall health (p<0.0001), being unmarried (p<0.0195) and lower baseline CES-D score (p<0.0001). Baseline sexual function and urinary control were not correlated with longitudinal CES-D scores. Similar factors were found to be correlated with SF-36 emotional well-being, energy and vitality scores. CONCLUSIONS: Treatment with surgery or radiation was not associated with depression symptoms, or emotional well-being, energy, and vitality scores when compared to active surveillance through five years. Factors associated with development of declining mental health included: older age, being unmarried, poor overall health and lower baseline scores. Further analysis is warranted to determine if post-treatment sexual, urinary and bowel function are associated with longitudinal changes in mental health.

MP67-18 IMPACT OF TREATMENT MODALITY ON OVERALL SURVIVAL IN LOCALIZED DUCTAL PROSTATE ADENOCARCINOMA: A NATIONAL CANCER DATABASE ANALYSIS