Open AccessMultidrug Resistance Among New Tuberculosis Cases
Author(s) -
Bethany L. Hedt,
Frank van Leth,
Matteo Zignol,
Frank Cobelens,
Wayne van Gemert,
Nguyen Viet Nhung,
Svitlana Lyepshina,
Saidi Egwaga,
Ted Cohen
Publication year - 2012
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0b013e3182459455
Subject(s) - tuberculosis , multiple drug resistance , medicine , resistance (ecology) , drug resistance , biology , microbiology and biotechnology , pathology , ecology
Current methodology for multidrug-resistant tuberculosis (MDR TB) surveys endorsed by the World Health Organization provides estimates of MDR TB prevalence among new cases at the national level. On the aggregate, local variation in the burden of MDR TB may be masked. This paper investigates the utility of applying lot quality-assurance sampling to identify geographic heterogeneity in the proportion of new cases with multidrug resistance.