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Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease. By 2020, COPD will become the third leading cause of death. Eosinophil is a component of T-helper 2 cell-mediated immunity and has an arsenal of antimicrobial defenses. A large quantity of eosinophils are released into the blood circulation from bone marrow after inflammation and they will be recruited to the airway and other tissues through chemokinemediated chemotaxis to initiate and upregulate the immune response [Figure 1].

Blood eosinophil level to predict chronic obstructive pulmonary disease clinical outcomes