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This study explores the use of bilaminar coculture pellets of mesenchymal stem cells (MSCs) and nucleus pulposus cells (NPCs) as a cell-based therapy for intervertebral disc regeneration. The pellets were tested under conditions that mimic the degenerative disc.

Structured Bilaminar Coculture Outperforms Stem Cells and Disc Cells in a Simulated Degenerate Disc Environment