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The presence of the A118G single nucleotide polymorphism in the OPRM1 gene as well as noxious stimulation might affect the requirements of remifentanil for patients undergoing ultrasonographic endoscopy under sedation-analgesia with propofol and remifentanil. Bispectral index (BIS) was used as a surrogate measure of effect.

anesthesiology

Modeling the Influence of the A118G Polymorphism in the <i>OPRM1</i> Gene and of Noxious Stimulation on the Synergistic Relation between Propofol and Remifentanil

Modeling the Influence of the A118G Polymorphism in the OPRM1 Gene and of Noxious Stimulation on the Synergistic Relation between Propofol and Remifentanil