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Inflammation of the dorsal root ganglia (DRG) may contribute to low back pain, postherpetic neuralgia, and neuropathic pain. The mineralocorticoid receptor (MR) plays a proinflammatory role in many nonrenal tissues, but its role in peripheral pain at the DRG level is not well studied.

anesthesiology

Mineralocorticoid Receptor Blocker Eplerenone Reduces Pain Behaviors <i>In Vivo</i> and Decreases Excitability in Small-diameter Sensory Neurons from Local Inflamed Dorsal Root Ganglia <i>In Vitro</i> 

Mineralocorticoid Receptor Blocker Eplerenone Reduces Pain Behaviors In Vivo and Decreases Excitability in Small-diameter Sensory Neurons from Local Inflamed Dorsal Root Ganglia In Vitro