Open AccessNitrous Oxide Diffusion and the Second Gas Effect on Emergence from Anesthesia
Author(s) -
Philip J. Peyton,
Ian Chao,
Laurence Weinberg,
Gavin J. B. Robinson,
Bruce Thompson
Publication year - 2011
Publication title -
anesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.874
H-Index - 234
eISSN - 1528-1175
pISSN - 0003-3022
DOI - 10.1097/aln.0b013e318209367b
Subject(s) - nitrous oxide , sevoflurane , anesthesia , medicine , anesthetic , arterial blood , partial pressure , minimum alveolar concentration , bispectral index , oxygen , chemistry , propofol , organic chemistry
Rapid elimination of nitrous oxide from the lungs at the end of inhalational anesthesia dilutes alveolar oxygen, producing "diffusion hypoxia." A similar dilutional effect on accompanying volatile anesthetic agent has not been evaluated and may impact the speed of emergence.
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