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THE 2010 Excellence in Research Award has been presented to J. A. Jeevendra (Jeeva) Martyn in recognition of his exceptional career of scientific inquiry and endeavor. Dr. Martyn is Director of the Clinical and Biochemical Pharmacology Laboratory of the Department of Anesthesia at Massachusetts General Hospital and Shriners Hospital for Children, Anesthetist-in-Chief at the Shriners Hospital for Children in Boston, and Professor of Anesthesia at Harvard Medical School. The highest recognition that can be bestowed by the American Society of Anesthesiologists, this award represents the pinnacle of professional achievement, acknowledging the designee for research of an original, sustained, clinically relevant, and lasting nature. Dr. Martyn is an outstanding anesthetist cum intensivist who has profoundly influenced the science and practice of anesthesiology and critical care medicine. In his role as clinical investigator, he has revolutionized the care of burn patients, a discipline in intensive care medicine that is not practiced extensively by anesthesiologists. He is a world authority on disease-induced up-regulation and down-regulation of the acetylcholine receptor in muscle and its interaction with agonist and antagonist drugs. He has contributed most of what we know about the molecular mechanisms of critical illness–induced insulin resistance, with the therapeutic goal of correcting the muscle wasting and associated disuseinduced muscle atrophy. Finally, he is the world’s leading authority on the clinical therapeutics of critically ill burned patients. Arthur Keats’ Rovenstine Lecture (1983) referred to the view of Myron Laver (1926–1982) (Late Professor at Harvard Medical School and Massachusetts General Hospital) that anesthesiology was at its best when observations made on a sample of patients could be applied to a broader class, thereby contributing to the benefit of medicine at large. This sentiment aptly describes the most defining aspect of Dr. Martyn’s work. Throughout his career, he has applied his clinical interest and personal observations to define clinically important questions identified in the operating room or intensive care unit and then used these observations as the impetus to create and guide laboratory studies to define mechanisms and improve care. To accomplish his goals, he often has transformed himself as a scientist by learning and applying a myriad of new techniques. Most of his findings, usually arising from observations in the burn population, have led back to the bedside, where they have proved beneficial to a much broader spectrum of patients than originally envisioned. This approach epitomizes the goals of modern investigative medicine. Dr. Martyn was born in Sri Lanka and received his medical degree from the University of Colombo, Sri Lanka, before coming to the United States. Having completed his residency in Anesthesiology at the College of Physicians and Surgeons, Columbia University-Presbyterian Hospital, he extended his training at the Radcliffe Infirmary and the University of Oxford, England. After a formal National Institutes of Health–sponsored postdoctoral research training fellowship, his self-directed evolution as a research scientist and academic career commenced. He has spent his entire posttraining career at Massachusetts General Hospital and Shri* Henry Isaiah Dorr Professor of Anesthesiology, Harvard Medical School, Boston, Massachusetts, Anesthetist-in-Chief, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Joseph Adrian Jeevendra Martyn, M.D., F.R.C.A., F.C.C.M., Recipient of the 2010 Excellence in Research Award