Open AccessAssociation between Epidural Analgesia and Cancer Recurrence after Colorectal Cancer Surgery
Author(s) -
Antje Gottschalk,
Justin G. Ford,
Cedric C. Regelin,
Jing You,
Edward J. Mascha,
Daniel I. Sessler,
Marcel E. Durieux,
Edward C. Nemergut
Publication year - 2010
Publication title -
anesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.874
H-Index - 234
eISSN - 1528-1175
pISSN - 0003-3022
DOI - 10.1097/aln.0b013e3181de6d0d
Subject(s) - medicine , perioperative , colorectal cancer , cancer , retrospective cohort study , surgery , breast cancer , prostate cancer , hazard ratio , cancer recurrence , proportional hazards model , cancer registry , anesthesia , confidence interval
Animal studies suggest that regional anesthesia and optimal postoperative analgesia independently reduce cancer metastasis. Retrospective clinical studies suggest reductions in recurrence of several cancer types in patients receiving perioperative neuraxial analgesia. Thus, the authors determined the association between perioperative epidural analgesia and cancer recurrence in patients undergoing colorectal cancer surgery.
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