Open AccessAmitriptyline Suppresses Neuroinflammation-dependent Interleukin-10-p38 Mitogen-activated Protein Kinase-Heme Oxygenase-1 Signaling Pathway in Chronic Morphine-infused Rats
Author(s) -
Yueh-Hua Tai,
RuYin Tsai,
ShinnLong Lin,
ChunChang Yeh,
JhiJoung Wang,
PaoLuh Tao,
ChihShung Wong
Publication year - 2009
Publication title -
anesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.874
H-Index - 234
eISSN - 1528-1175
pISSN - 0003-3022
DOI - 10.1097/aln.0b013e31819fccd5
Subject(s) - amitriptyline , morphine , pharmacology , medicine , heme oxygenase , zinc protoporphyrin , p38 mitogen activated protein kinases , protein kinase a , kinase , chemistry , heme , biochemistry , enzyme
This study explores the underlying mechanism of the antiinflammatory effect of amitriptyline in chronic morphine-infused rats.
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