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The effects of hypercapnic acidosis on the diaphragm and its recovery to normocapnia have been poorly evaluated. The authors studied diaphragmatic contractility facing acute variations of arterial carbon dioxide tension (Paco2) and evaluated the contractile function at 60 min after normocapnia recovery.

Alteration of the Piglet Diaphragm Contractility In Vivo and Its Recovery after Acute Hypercapnia