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32. Gaskell AL, Hight DF, Winders J, Tran G, Defresne A, Bonhomme V, Raz A, Sleigh JW, Sanders RD: Frontal alphadelta EEG does not preclude volitional response during anaesthesia: Prospective cohort study of the isolated forearm technique. Br J Anaesth 2017; 119:664–73 33. McCarthy MM, Brown EN, Kopell N: Potential network mechanisms mediating electroencephalographic beta rhythm changes during propofol-induced paradoxical excitation. J Neurosci 2008; 28:13488–504 34. Thompson GJ, Pan WJ, Billings JC, Grooms JK, Shakil S, Jaeger D, Keilholz SD: Phase-amplitude coupling and infraslow (<1 Hz) frequencies in the rat brain: Relationship to resting state fMRI. Front Integr Neurosci 2014; 8:41 35. Blain-Moraes S, Lee U, Ku S, Noh G, Mashour GA: Electroencephalographic effects of ketamine on power, cross-frequency coupling, and connectivity in the alpha bandwidth. Front Syst Neurosci 2014; 8:114 36. Blain-Moraes S, Tarnal V, Vanini G, Alexander A, Rosen D, Shortal B, Janke E, Mashour GA: Neurophysiological correlates of sevoflurane-induced unconsciousness. ANESTHESIOLOGY 2015; 122:307–16 37. Dutta S, Lal R, Karol MD, Cohen T, Ebert T: Influence of cardiac output on dexmedetomidine pharmacokinetics. J Pharm Sci 2000; 89:519–27 38. Franks NP: General anaesthesia: From molecular targets to neuronal pathways of sleep and arousal. Nat Rev Neurosci 2008; 9:370–86

From Benzene Rings to Political Ones: Metz and His Benzocaine, Anaesthesine