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results: Eighty-six patients were included. Mean age at initial presentation was 69.4 years. Mean follow-up was 6.4 years. Estimated overall survival was 88% and 57% at 5 and 10 years respectively. Recurrence-free survival was 67% and 50% at 5 and 10 years respectively. Rate of metastasis was 3.5%. Lymph node biopsy was performed in 4 cases with clinically abnormal lymph node exam with 2 positive results. Average time to first recurrence was 4.1 years. Webspace location, bilateral tumors, multiple number, and prior history of SCC were among factors with increased risk for recurrence. Survival free of SCC in the same upper extremity was 72% and 54% at 5 and 10 years respectively. Younger age, history of transplantation, multiple number, and use of flap or skin graft for closure were among factors associated with increased risk of same extremity SCC development. No significant difference was noted among different treatment modalities for overall survival, recurrencefree survival, or SCC occurrence in the same upper extremity.

A Long Term Review of Squamous Cell Carcinoma in the Hand