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RESULTS: The cohort was 50.8% male and with an average age of 59.0 ± 18.0 years and body mass index of 27.8 ± 6.7 kg/ m. In 85% of cases, ≥1 drain was in intimate contact with the hardware and/or bone graft, and patients received no >24 hours of postoperative intravenous cefazolin (or other appropriate perioperative coverage in case of documented allergy) unless further antibiotics were indicated. There were 15 cases of SSI, overall, making for an incidence of 4.9%. Drain durations were clearly documented in 271 cases. Median drain dwell duration among these cases was 19 days (interquartile range [IQR], 14–27 days), overall, 19 days (IQR, 14–27 days) among cases which did not develop SSI, and 22 days (IQR, 15–30 days) among cases which did develop SSI (P = 0.231). Univariable logistic regression analysis also demonstrated no increased risk with longer drain dwell times for the development of SSI (odds ratio [OR], 1.03; 95% confidence interval [CI], 0.98–1.08; P = 0.282), wound complication requiring reoperation (OR, 1.02; 95% CI, 0.96–1.09; P = 0.559), or subsequent removal of hardware due to infection (OR, 1.03; 95% CI, 0.95–1.11; P = 0.528).

Mechanism of Skin Improvement in Radiation Wounds Following Fat Grafting: The Fate of Adipose-derived Stem Cells and Role of Stromal Vascular Fraction