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processes. A major strength of the zebrafish model system is the ability to image live embryos and visualize multiple stages of early development in vivo. Fate-mapping of irf6-expressing cells at different time points in zebrafish embryos using the dual reporter line will be critical in studying the interactions of epithelial and chondrocyte cells during palate morphogenesis. As new developments in gene and cellular therapies are pursued, understanding the basic transcriptional circuits is essential in designing genomic targets for gene therapy, or in the engineering of bioactive implantable materials for optimal surgical outcomes.

Abstract 5: Inhibition of Mechanotransduction Yields Regenerative Wound Healing by Engrailed1-negative Fibroblasts