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CONCLUSION: Patients with extensive lower extremity soft tissue defects often require plastic surgery soft tissue reconstruction after sarcoma resection. Based on our results, in patients that cannot undergo primary closure, local flaps can effectively reconstruct the majority of lower extremity sarcoma defects. However, microvascular free tissue transfer may be warranted for large wounds, areas of previous irradiation damage, or in the distal lower extremity. The post-operative management of sarcoma patients remains challenging due to high rates of wound complications. Local recurrence and metastatic disease confer additional morbidity and mortality in this patient population.

Abstract: Efficacy of Neuroma Excision for Treatment of Severe Neuropathic Burn Pain