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RESULTS: Sixteen staged breast reductions (eight patients) were identified that were performed at an average of 5.2 months (range: 3.0–6.8) prior to NSM. Wise-pattern skin excision was utilized in 14 cases (87.5%) and vertical in 2 cases (12.5%) with medial (8 cases, 50%) or superomedial (8 cases) pedicles and an average reduction weight of 407 grams (range: 82–1240). Subsequently, 32 non-staged NSMs (26 patients) were identified that met inclusion criteria as matches for specific complication risk factors. There were no significant differences between staged and non-staged groups with regards to age (44.1 versus. 43.9, respectively; p=0.9960) and body mass index (25.0 versus 25.6, respectively; p=0.5648). All NSMs in both groups were prophylactic cases. There were no cases with preor postoperative radiation and no patients with tobacco use at the time of NSM in either group. There were no significant differences in mastectomy incisions, the majority of which were inframammary incisions (12 [75%] in the staged cohort and 28 [84.4%] in the non-staged cohort; p=0.3585).

Abstract: Comparing the Surgical Outcomes of Prophylactic and Therapeutic Mastectomies with Immediate Reconstruction