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CONCLUSION: This study investigates the use of an FK506-impregnated PEUU nerve wrap to improve functional recovery following peripheral nerve injury. Sensory testing provides objective data on the effects of these wraps in the treatment of peripheral nerve injuries and the FK wraps appear to accelerate nerve recovery at 4 weeks, with minimal systemic drug exposure. The findings from this study may translate into novel treatment systems and protocols to treat nerve injuries.

Abstract: Electrical Stimulation As a Conditioning Lesion for Promoting Peripheral Nerve Regeneration