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PURPOSE: The ability of deferoxamine (DFO) to mitigate the deleterious effects of radiation on bone healing and regeneration for head and neck cancer (HNC) reconstruction is currently being investigated. However, there remains concern about the tumorigenic potential of DFO, due to the ability of DFO to induce angiogenesis and promote tissue vascularization. The purpose of this study is to investigate the effects of DFO on head and neck squamous cell carcinoma (HNSCC) in-vitro and in-vivo, to delineate the clinical safety of DFO administration to HNC patients.

Abstract 106: Impact of Diabetes On Microsurgical Free Tissue Transfer Outcomes: Analysis Of 6,030 Cases