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Treatment goal in cutaneous squamous cell carcinoma (SCC) is complete removal of the tumor with clear histological margins. Gold nanoparticles (GNPs) can be distributed to a tumor by conjugating them with an antibody specific to the tumor’s surface receptor. The consequent change in the optical properties of the cancerous tissue distinguishes it from normal tissue. Given that about 90% of SCCs overexpress epithelium-derived growth factor (EGFR), we sought to determine the sensitivity of diffusion reflection spectroscopy measurements of SCC targeted by GNPs bio-conjugated to anti-EGFR antibodies in identifying residual tumor in excision borders.

plastic and reconstructive surgery. global open

Abstract: 8.40 Retrospective Data Analysis In Breast Cancer Patients After Skin-Sparing Or Nipple-Sparing Mastectomy Prove Efficiency And Sustainability Of This Breastconserving Therapy