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A large animal model for composite face transplantation is necessary to better understand the immunologic processes and nerve regeneration. Current porcine models of facial transplantation fail to include all major branches of the facial nerve, and have not demonstrated long-term survival.1,2 A better understanding and detailed evaluation of vascular anatomy and microvascular territories in facial subunits and bone can help effectively develop a reliable porcine composite tissue flap model for experimental reconstructive or transplantation studies.

plastic and reconstructive surgery. global open

Abstract: Vascular Anatomy of Facial Units for Vascularized Composite Tissue Transplantation Design in a Large Animal Model: An in-Vivo and Radiological Study