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Pulmonary diffusing capacity for carbon monoxide (Dlco), alveolar-capillary membrane diffusing capacity (Dm), and pulmonary capillary blood volume (Vc) are all significandy reduced following exercise. It is unknown if measurement position affects this impaired gas transfer postexercise. Prior to (baseline) and 15 minutes, 1, 2, and 4 hours following an incremental cycle to fatigue Dlco, Dm, and Vc were recorded in 10 healthy male subjects in both a supine and upright seated position. It was expected that the supine post-exercise measurement position would significantly reduce the decrement in Vc and thus Dlco, by facilitating a return of blood to the thoracic cavity. With removal of the 15 minute data, due to the lack of achievement of a resting cardiovascular state (heart rate, systolic and diastolic blood pressure all significantly different from baseline), a significant reduction in Dlco, Dm, and Vc was observed 1, 2, and 4 hours postexercise, as indicated in Table 1. Table 1. Dlco, Dm, and Vc mean values for supine and seated combined corrected for alveolar volume. Baseline 1 hr 2 hrs 4 hrs Dlco 5.51+1.03 4.72+0.94* 4.76+0.87* 4.79+0.89* (ml.rnin̂ .rnmHg" .L") Dm 7.09+1.19 6.11+0.31* 6.24+1.06* 6.20+1.03* (rm.rrin"\mrnHg" Vc 15.09+4.91 12.80+3.98* 12.07+3.74* 12.76+3.89* (ml.L) * significantly different compared with baseline (p<0.05)

CAN ALTERED BODY POSITION ALLEVIATE THE POST-EXERCISE PULMONARY DIFFUSING CAPACITY IMPAIRMENT?