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Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is a newly discovered virus found in all forms of KS. In the United States, KSHV infection appears to be most common amongst individuals at high-risk for KS. Preliminary data from Africa suggest that KSHV infection may be much more common in the general population.

Increasing Kaposiʼs sarcoma-associated herpesvirus seroprevalence with age in a highly Kaposiʼs sarcoma endemic region, Zambia in 1985