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Sleep is altered in most neural disorders including Alzheimer's disease, Parkinson's, and epilepsy. This may present as reduced sleep depth, altered proportions of rapid eye movement sleep (REM), and non-REM sleep (NREM), and other phenomena. In epilepsy, poor sleep can trigger seizures, which further disrupt sleep. We therefore speculate that improving sleep quality could alleviate seizures. To this end, we characterized the effects of acute changes in cage temperature Ta on sleep in a mouse model of chronic epilepsy.

0094 SLEEP MODULATION IN CONTROL AND EPILEPTIC MICE THROUGH AMBIENT TEMPERATURE REGULATION